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Red flag symptoms ²,⁶

Signs to watch for and document before your first appointment. The more specifically you can describe when each appeared, the more useful your observations will be.

Behavioral and emotional

  • Sudden severe OCD or compulsive rituals: checking, counting, repeating phrases, arranging objects
  • Intense new separation anxiety or extreme fear of being alone
  • Rage episodes or aggression that are dramatically out of proportion to the situation
  • Emotional lability: cycling rapidly between sadness, fear, and anger within minutes
  • Personality change that feels like someone else is inhabiting your child

Physical and functional

  • New urinary urgency, very frequent bathroom trips, or regression to bedwetting
  • Handwriting that has noticeably changed, become smaller, or regressed
  • New food restriction, sudden refusal of foods they previously accepted, or severely reduced appetite
  • New motor or vocal tics: repetitive movements, blinking, throat clearing, sniffing, or sounds

Cognitive and sensory

  • Math ability, reading, or memory that has noticeably declined
  • New sensory sensitivities to loud sounds, bright lights, clothing textures, or physical touch
  • Difficulty organizing thoughts, completing sentences, or following instructions they previously managed easily

Sleep

  • Insomnia or significant difficulty falling or staying asleep
  • Nighttime fears or terror that are new or dramatically worse
  • Inability to sleep alone after months or years of doing so
  • Unusual waking in the night with distress

A note on documentation

If you are seeing several of these signs, start keeping a simple log: date, what you observed, and whether anything else was happening (illness, stress, a change in routine). The PANS/PANDAS Companion is built for exactly that. Specificity matters when you are talking to a clinician who may not yet be familiar with PANS or PANDAS.

Next step

Take the 2-minute screener. It will organize what you have observed into a format your doctor can use.

Not medical advice. This content is for orientation only. Diagnosis requires a trained clinician. If your child is in acute distress, contact your provider or go to the nearest emergency room.